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hímzés második Akar overall mutation load and p53 mutations Szüksége van Impresszionizmus vágta

Diverse rescue potencies of p53 mutations to ATO are predetermined by  intrinsic mutational properties | Science Translational Medicine
Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties | Science Translational Medicine

Prognostic value of TP53 mutation location in breast cancer | CMAR
Prognostic value of TP53 mutation location in breast cancer | CMAR

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral  and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

TP53 exon-6 truncating mutations produce separation of function isoforms  with pro-tumorigenic functions | eLife
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions | eLife

Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune  escape through PHLPP2/AKT/PD-L1 pathway
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway

Frequency of p53 mutations in human cancers. (A) Schematic picture... |  Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome:  Cell
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell

Mutations in TP53 and other heterogeneous genes help to distinguish  metastases from new primary malignancies | medRxiv
Mutations in TP53 and other heterogeneous genes help to distinguish metastases from new primary malignancies | medRxiv

TP53 mutation spectrum in primary colorectal cancers. a Proportion of... |  Download Scientific Diagram
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram

Homogenous TP53mut-associated tumor biology across mutation and cancer  types revealed by transcriptome analysis | Cell Death Discovery
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery

Acetylation halts missense mutant p53 aggregation and rescues tumor  suppression in non-small cell lung cancers - ScienceDirect
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers - ScienceDirect

High prevalence of TP53 loss and whole-genome doubling in early-onset  colorectal cancer | Experimental & Molecular Medicine
High prevalence of TP53 loss and whole-genome doubling in early-onset colorectal cancer | Experimental & Molecular Medicine

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Gastrointestinal Disorders | Free Full-Text | Prognostic Impact of TP53  Mutations and Tumor Mutational Load in Colorectal Cancer
Gastrointestinal Disorders | Free Full-Text | Prognostic Impact of TP53 Mutations and Tumor Mutational Load in Colorectal Cancer

Evaluating the prognostic significance of p53 and TP53 mutations in  HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up  retrospective study | BMC Cancer | Full Text
Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study | BMC Cancer | Full Text

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Overall survival curves of patients with p53 mutation results. (A) p53... |  Download Scientific Diagram
Overall survival curves of patients with p53 mutation results. (A) p53... | Download Scientific Diagram

Survival of patients with p53 mutations in the DNA-binding motifs... |  Download Scientific Diagram
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

TP53 mutations predict poor response to immunotherapy in patients with  metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online  Library
TP53 mutations predict poor response to immunotherapy in patients with metastatic solid tumors - Kim - 2023 - Cancer Medicine - Wiley Online Library

Gain of function in somatic TP53 mutations is associated with immune‐rich  breast tumors and changes in tumor‐associated macrophages - Behring - 2019  - Molecular Genetics & Genomic Medicine - Wiley Online Library
Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages - Behring - 2019 - Molecular Genetics & Genomic Medicine - Wiley Online Library

Low-burden TP53 mutations in CLL: clinical impact and clonal evolution  within the context of different treatment options - ScienceDirect
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options - ScienceDirect

The p53 network: cellular and systemic DNA damage responses in cancer and  aging: Trends in Genetics
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics

Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with  the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes

Mutational processes shape the landscape of TP53 mutations in human cancer  | Nature Genetics
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics